Diarrhea | Grade 1 | Grade 2 | Grade 3 | Grade 4 |
|---|
End of RT | 28.2% | 2.6% | - | - |
13 weeks | 7.9% | - | - | - |
6 months | - | 2.7% | - | - |
12 months | 2.7% | - | - | - |
18 months | - | - | - | - |
24 months | - | - | - | - |
Enteritis
|
Grade 1
|
Grade 2
|
Grade 3
|
Grade 4
|
End of RT | 15.4% | - | - | - |
13 weeks | - | 7.9% | - | - |
6 months | - | 5.4% | - | - |
12 months | - | - | - | - |
18 months | 31.% | - | - | - |
24 months | - | 4.5% | - | - |
Proctitis
|
Grade 1
|
Grade 2
|
Grade 3
|
Grade 4
|
End of RT | 17.9% | 12.8% | - | - |
13 weeks | 10.5% | - | - | - |
6 months | 2.7% | 2.7% | - | - |
12 months | - | - | - | - |
18 months | - | - | 3.1% | - |
24 months | - | - | - | - |
- Diarrhea: CTC AE grade 1 = increase < 4 stools per day over baseline; grade 2 = increase 4-6 stools per day; grade 3 = increase ≥ 7 stools per day or incontinence or hospitalisation or limiting self care ADL; grade 4 = life-threatening consequences, urgent intervention indicated.
- Enteritis: CTC AE grade 1 = asymptomatic; grade 2 = abdominal pain, mucus or blood in stool; grade 3 = severe or persistent abdominal pain, fever, ileus, peritoneal signs; grade 4 = life-threatening consequences, urgent intervention indicated.
- Proctitis: CTC AE grade 1 = rectal discomfort, intervention not indicated; grade 2 = symptoms (e.g. rectal discomfort, passing blood or mucus), medical intervention, limiting instrumental ADL; grade 3 = severe symptoms, fecal urgency or stool incontinence, limiting self care ADL; grade 4 = life-threatening consequences, urgent intervention indicated.
