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Figure 5 | BMC Cancer

Figure 5

From: Novel transcripts from a distinct promoter that encode the full-length AKT1 in human breast cancer cells

Figure 5

AKT1m transcripts are expressed and upregulated in a subset of human breast cancer cell lines. Quantitative real-time RT-PCR analysis to assess the relative transcriptional activation of the AKT1m transcripts in a panel of three untransformed human breast epithelial cell lines and 38 breast cancer cell lines that represent all major subtypes of this malignancy (i.e., ERα-positive, ErbB2-positive, and triple-negative). Each sample was examined in triplicate and normalized to GAPDH expression. The expression of AKT1m in untransformed MCF-10A cells was set to 1.0 and statistical analysis was performed for each cell line relative to the MCF-10A control; t test *P < 0.05, **P < 0.01.

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