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Table 2 Details about each core on the TMA slide

From: Functional proteomic analysis reveals the involvement of KIAA1199 in breast cancer growth, motility and invasiveness

Core

Breast cancer type

Sex

Age

Tissue area

Threshold (%)

Log2*

a1

Phyllodes Tumor

F

45

271599

0.15

−2.72

b1

Non-neoplastic

F

45

254568

0.12

−3.04

a2

Infiltrating Ductal Carcinoma

F

58

332807

1

0

b2

Non-neoplastic

F

58

191591

0

−9.32

a3

Invasive Lobular Carcinoma

F

51

326860

3.12

1.64

b3

Non-neoplastic

F

51

247173

0.64

−0.65

a4

Infiltrating Ductal Carcinoma

F

66

332029

18.21

4.19

b4

Non-neoplastic

F

66

143861

0.01

−6.68

a5

Infiltrating Ductal Carcinoma

F

54

373279

0.54

−0.88

b5

Non-neoplastic

F

54

277105

0.16

−2.65

c1

Infiltrating Ductal Carcinoma

F

55

340233

8.12

3.02

d1

Non-neoplastic

F

55

83421

0

−8.7

c2

Infiltrating Ductal Carcinoma

F

63

273915

1.44

0.53

d2

Non-neoplastic

F

63

270038

2.87

1.52

c3

Atypical Medullary Carcinoma

M

72

306756

0.02

−5.88

d3

Non-neoplastic

M

72

195427

0.07

−3.84

c4

Infiltrating Ductal Carcinoma

F

64

358767

23.08

4.53

d4

Non-neoplastic

F

64

215357

0

−11.07

c5

Atypical Medullary Carcinoma

F

49

253762

0.02

−5.45

d5

Non-neoplastic

F

49

304971

0.18

−2.51

e1

Infiltrating Ductal Carcinoma

F

38

355620

7.01

2.81

f1

Non-neoplastic

F

38

260062

0.1

−3.38

e2

Infiltrating Ductal Carcinoma

F

41

381085

0.87

−0.2

f2

Non-neoplastic

F

41

30471

0.19

−2.37

  1. *p-value = 0.025, T-test = 2.581.
  2. The IHC staining of 12 tumor and 12 non-neoplastic tissues cores on the TMA slide (Figure 1) was evaluated based on log2 of%Threshold. The T-test showed the significant difference of KIAA1199 expression between non-neoplastic breast tissues and breast tumor tissues (overall 14.66 fold overexpression of KIAA1199 in tumor tissues).