Figure 4

KIAA1199 Knockdown inhibited tumorigenicity, growth and neovascularization. A) The relative tumor incidence in MDA-MB-231-ShNC and MDA-MB-231-ShB cell bearing mice; The MDA-MB-231-ShNC (control) and MDA-MB-231-ShB cells were implanted into the mammary fat pads of two groups of nude mice (n = 5). Four of the MDA-MB-231-ShNC and one of the MDA-MB-231-ShB implanted mice developed tumors. B) Tumor growth diagram for MDA-MB-231-ShNC and MDA-MB-231-ShB injected mice.