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Figure 10 | BMC Cancer

Figure 10

From: Norcantharidin inhibits tumor growth and vasculogenic mimicry of human gallbladder carcinomas by suppression of the PI3-K/MMPs/Ln-5γ2 signaling pathway

Figure 10

Expression of VM signal-related proteins/mRNAs PI3-K, MMP-2, MM1-MMP and Ln-5γ2 of GBC-CD xenografts in vivo . (A) Western blotting: Overexpression of PI3-K, MMP-2, MM1-MMP and Ln-5γ2 proteins of GBC-SD xenografts in control group was observed; but expression of these proteins in TIMP-2 or NCTD group was significantly decreased (*P < 0.001, vs. control group). (B) RT-PCR: Expression of PI3-K, MMP-2, MM1-MMP and Ln-5γ2 mRNAs of GBC-SD xenografts in control group was increased significantly when compared with TIMP-2 and NCTD groups (*P < 0.01).

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BMC Cancer

ISSN: 1471-2407

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