Preoperative chemoradiotherapy in rectal cancer induces changes in the expression of nuclear β-catenin: prognostic significance

Table 4 β-catenin and E-cadherin expression before and after RT-CT

β-catenin-E-cadherin expression	PRE RT-CT		POST RT-CT		P
	Patients		Patients
	N (69)	%	N (69)	%
Nuclear β-catenin score					P=0.001
Absent	33	48%	23	33%
Low	21	30%	19	28%
Moderate	12	17%	15	22%
High	3	4%	12	17%
Membranous E-cadherin score					P=0.13
Absent	2	3%	5	7%
Low	1	1%	1	1%
Moderate	11	16%	8	12%
High	16	23%	24	35%
Very high	39	57%	31	50%

β-catenin. Absent: Absence of cells expressing β-catenin; Low: Less than 25% of cells; Moderate: Between 25% and 75% of cells; High: More than 75% of cells. E-cadherin. Absent: Absence of cells expressing E-cadherin. Low: Less of 25% of cells expressing E-cadherin. Moderate: Between 25% and 75% of cells expressing E-cadherin. High: More than 75% of cells expressing E-cadherin. Very high: 100% of cells expressing E-cadherin.

ISSN: 1471-2407