Preoperative chemoradiotherapy in rectal cancer induces changes in the expression of nuclear β-catenin: prognostic significance

Table 2 Distribution of nuclear β-catenin and E-cadherin relative to different clinicopathological prognostic factors

Prognostic factors	All patients		E-cadherin				P	Nuclear β-catenin				P
			Absence vs. presence					Absence vs. presence
	N	%	N	%	N	%		N	%	N	%
	98	100	46	47%	52	53%		74	76%	24	24
Sex
Male	72	73%	33	46%	39	54%	P=0.4	56	78%	16	22%	P=0.4
Female	26	27%	13	50%	13	50%	P=0.4	18	69%	8	31%	P=0.4
Age												P=0.9
</= 50	48	49%	9	64%	36%	5	P=0.6	10	71%	4	29%
>50	50	51%	37	44%	47	56%	P=0.6	64	76%	20	24%
Distance to anal margin												P=0.7
</= 5 cm	84	86%	22	46%	26	54%	P=0.8	38	79%	10	21%
>5 cm	14	14%	24	48%	26	52%	P=0.8	36	72%	14	28%
T stage												P=0.4
T2-3	82	83%	38	47%	42	53%	P=0.8	59	74%	21	26%
T4	17	17%	8	44%	10	56%	P=0.8	15	83%	3	17%
N stage												P=0.2
N-	43	44%	19	43%	25	57%	P=0.5	19	43%	25	57%
N+	55	56%	27	50%	37	50%	P=0.5	22	41%	32	59%
TGR*												P=0.6
TGR 1-2	44	45%	18	41%	26	59%	P=0.2	32	73%	12	27%
TGR 3-5	54	55%	28	52%	26	48%		42	78%	12	22%
pN ††							P=0.8					P=0.9
pN-	70	71%	20	74%	7	26%		30	44%	41	56%
pN+	28	29%	54	76%	17	24%		11	41%	16	59%

ISSN: 1471-2407