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Table 2 Correlation between overexpression of ezrin, ezrin Thr-567 and ezrin Tyr-353 proteins and clinical parameters of NSCLC

From: Prognostic implications of ezrin and phosphorylated ezrin expression in non-small cell lung cancer

 

Ezrin

EzrinThr-567

EzrinTyr-353

Parameters

No. of cases

n(%)

P

n(%)

P

n(%)

P

Gender

  

0.062

 

0.45

 

0.230

  Male

112

75 (67.0)

69 (61.6)

77 (68.8)

  Female

38

19 (50.0)

26 (68.4)

30 (78.9)

Age

  

0.077

 

0.642

 

0.364

  ≧60

99

67 (67.7)

64 (64.6)

73 (73.7)

  <60

51

27 (52.9)

31 (60.8)

34 (66.7)

Tumor size

  

0.283

 

.791

 

0.620

  T1-2

119

72 (60.5)

76 (63.9)

86 (72.3)

  T3-4

31

22 (71.0)

19 (61.3)

21 (67.7)

Stage

  

0.000**

 

.031*

 

0.000**

  I-II

98

51 (52.0)

56 (57.1)

59 (60.2)

  III-IV

52

43 (82.7)

39 (75.0)

48 (92.3)

Differentiation

  

0.007 a **

 

0.002 a **

 

0.006 a **

  Well

34

17 (50.0)

16 (47.1)

21 (61.8)

  Moderate

89

54 (60.7)

55 (61.8)

61 (68.5)

  Poor

27

23 (85.2)

24 (88.9)

25 (92.6)

LN metastasis

  

0.318

 

0.002**

 

0.578

  Negative

96

63 (65.6)

52 (54.2)

67 (69.8)

  Positive

54

31 (57.4)

43 (79.6)

40 (74.1)

  1. *P < 0.05; **P < 0.01; a: Poorly vs Well and moderately differentiated tumors.