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Table 1 Histopathological characteristics, tumor classification and EGFR genotypes in Brazilian breast cancer patients

From: Epidermal growth factor receptor gene polymorphisms are associated with prognostic features of breast cancer

Independent variables

n

%

Tumor classifications

n

%

Histological type

     

 Ductal invasive

440

8606

0

35

7.1

 Ductal in situ

34

6.7

IA

157

31.7

 Lobular in situ

1

0.2

IB

7

1.4

 Lobular invasive

29

5.7

II A

148

29.9

 Mixed

4

0.8

II B

70

14.1

   

III A

52

10.5

Tumor grade

  

III B

1

0.2

 Grade 1

60

12.6

III C

25

5.1

 Grade 2

193

40.5

missing

13

 

 Grade 3

223

46.8

   

 Missing

32

 

Biological classifiation

  
   

luminal A

293

64.8

Tumor size

  

luminal B

89

5.8

 pTis

35

7.1

HER2 like

26

5.8

 pT1

226

45.7

triple negative

44

9.7

 pT2

220

44.4

missing

56

 

 pT3

13

2.6

   

 pT4

1

0.2

ERR categories

  

Missing

13

 

low

20

4.2

   

intermediate

357

75.5

Lymph node status

  

high

96

20.3

 pN0

312

61.4

missing

35

 

 pN1

120

23.6

   

 pN2

50

9.8

   

 pN3

26

5.1

   

Estrogen receptor

  

EGFR Genotypes

n

%

 Negative

76

15.0

R497K

  

 Positive

414

84.5

Arg/arg

308

61.0

 Missing

18

 

Arg/Lys

176

34.9

   

Lys/Lys

21

4.2

Progesterone receptor

  

missing

3

 

 Negative

134

26.4

   

 Positive

355

72.6

   

 Missing

19

    
   

(CA)n

  

HER2

  

Short/Short

108

22.6

 Negative

378

74.4

Short/Long

230

48.2

 Indeterminate

15

3.2

Long/Long

139

29.1

 Positive

73

15.7

missing

31

 

 Missing

42

    
  1. Data are expressed as the number of patients and their respective percentage in each category. (CA)n Short: n≤ 16; (CA)n Long: n > 16. Abbreviations: ERR Estimated Recurrence Risk, HER2 Human Epidermal growth factor Receptor 2.