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Table 1 Histopathological characteristics, tumor classification and EGFR genotypes in Brazilian breast cancer patients

From: Epidermal growth factor receptor gene polymorphisms are associated with prognostic features of breast cancer

Independent variables n % Tumor classifications n %
Histological type      
 Ductal invasive 440 8606 0 35 7.1
 Ductal in situ 34 6.7 IA 157 31.7
 Lobular in situ 1 0.2 IB 7 1.4
 Lobular invasive 29 5.7 II A 148 29.9
 Mixed 4 0.8 II B 70 14.1
    III A 52 10.5
Tumor grade    III B 1 0.2
 Grade 1 60 12.6 III C 25 5.1
 Grade 2 193 40.5 missing 13  
 Grade 3 223 46.8    
 Missing 32   Biological classifiation   
    luminal A 293 64.8
Tumor size    luminal B 89 5.8
 pTis 35 7.1 HER2 like 26 5.8
 pT1 226 45.7 triple negative 44 9.7
 pT2 220 44.4 missing 56  
 pT3 13 2.6    
 pT4 1 0.2 ERR categories   
Missing 13   low 20 4.2
    intermediate 357 75.5
Lymph node status    high 96 20.3
 pN0 312 61.4 missing 35  
 pN1 120 23.6    
 pN2 50 9.8    
 pN3 26 5.1    
Estrogen receptor    EGFR Genotypes n %
 Negative 76 15.0 R497K   
 Positive 414 84.5 Arg/arg 308 61.0
 Missing 18   Arg/Lys 176 34.9
    Lys/Lys 21 4.2
Progesterone receptor    missing 3  
 Negative 134 26.4    
 Positive 355 72.6    
 Missing 19     
    (CA)n   
HER2    Short/Short 108 22.6
 Negative 378 74.4 Short/Long 230 48.2
 Indeterminate 15 3.2 Long/Long 139 29.1
 Positive 73 15.7 missing 31  
 Missing 42     
  1. Data are expressed as the number of patients and their respective percentage in each category. (CA)n Short: n≤ 16; (CA)n Long: n > 16. Abbreviations: ERR Estimated Recurrence Risk, HER2 Human Epidermal growth factor Receptor 2.