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Table 1 The frequency of EGFR, KRAS, PIK3CA and PTEN mutations according to different patterns (n = 38)

From: High-incidence of PTEN mutations in Chinese patients with primary small cell carcinoma of the esophagus

Patterns of mutations

No. of cases (%)

EGFR

 

Exon 18 (G719S)

0

Exon 19 (DEL)

0

Exon 20

 

T790M

0

INS

0

S7681

0

Exon 21

 

L858R

1 (2.63)

L861Q

0

KRAS

 

Codon 12

0

Codon 13

0

PIK3CA

 

Exon 9 (E542/545)

0

Exon 20 (H1047R)

0

PTEN

 

Exon 5

4 (10.53)

Exon 6

7 (18.42)

Exon 8

1 (2.63)

Exon 5 and Exon 6

2 (5.26)

  1. 2 patients also mutated in both Exon 5 and Exon 6 for PTEN.