Figure 1
From: Glucocorticoid receptor repression mediated by BRCA1 inactivation in ovarian cancer
GR expression patterns in non-mutated and BRCA1-mutated ovarian cancer. A, relative GR mRNA levels were measured in 28 pairs of non-mutated and BRCA1-mutated ovarian cancer and their adjacent normal tissue. Bar graphs show mean ± SD. B, GR protein levels assessed by immunohistochemistry in 28 pairs of non-mutated and BRCA1-mutated ovarian cancer and their adjacent normal tissue. Intensity of the staining was scored by division into 10 arbitrary units based on the Mean Density (see details in Methods: Immunohistochemistry).