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Table 1 KEGG Pathways significantly affected by mutant MLK3

From: Dissecting the signaling pathways associated with the oncogenic activity of MLK3 P252H mutation

KEGG

p-value

Odds

Exp count

Count

Size

Term

ID

 

Ratio

    

970

0.000

4.669

5

16

35

Aminoacyl-tRNA biosynthesis

290

0.001

7.682

2

7

12

Valine, leucine and isoleucine biosynthesis

5120

0.001

2.477

11

21

68

Epithelial cell signaling in Helicobacter pylori infection

251

0.004

3.184

5

11

30

Glutamate metabolism

630

0.009

4.693

2

6

13

Glyoxylate and dicarboxylate metabolism

4115

0.013

1.984

11

18

68

p53 signaling pathway

330

0.014

2.517

5

11

35

Arginine and proline metabolism

3020

0.018

2.923

4

8

23

RNA polymerase

5020

0.026

2.948

3

7

20

Parkinson's disease

670

0.027

3.283

2

6

16

One carbon pool by folate

5210

0.03

1.721

13

20

84

Colorectal cancer

600

0.031

2.155

6

11

39

Sphingolipid metabolism

260

0.038

1.995

7

12

45

Glycine, serine and threonine metabolism

5040

0.041

2.241

5

9

31

Huntington's disease

5110

0.044

2.01

6

11

41

Cholera - infection