Figure 4From: Analytical validation of the PAM50-based Prosigna Breast Cancer Prognostic Gene Signature Assay and nCounter Analysis System using formalin-fixed paraffin-embedded breast tumor specimens Overview of tissue processing for assessing the effect of tissue interferents. Multiple sections from FFPE breast tumor blocks were mounted onto slides and processed with or without macrodissection. The change in ROR score (ΔROR) is calculated as the ROR score from the non-macrodissected slides minus the ROR score from the macrodissected slides (or in the illustration ΔROR = 25 – 30 = -5).Back to article page