Effect of ShCCND1 on NCI-N87 cell cycle distribution and apoptosis determined by flow cytometry. ShCCND1 significantly increased the G1 distribution of the cell cycle compared to that of ShScramble (A). Apoptosis was significantly increased in ShCCND1 compared to that of ShScramble (B). The data presented are the mean ± SEM. **P < 0.01 and ***P < 0.001 versus the ShScramble-transduced cells.