Figure 4

Histological observation of early metastases after intra-tibial injection of A-673 ES cells. A-B: control mice treated with PBS: observation 7 days after tumor cell injection (A: CD99-, B: CD99+). C-D: ZA treated group: observation 7 days after tumor cell injection (C: CD99-, B: CD99+). The metastatic ES cells appear in brown on the CD99+ staining panels (B and D) (all magnitude: × 130).