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Figure 2 | BMC Cancer

Figure 2

From: Zoledronic acid inhibits pulmonary metastasis dissemination in a preclinical model of Ewing’s sarcoma via inhibition of cell migration

Figure 2

Effect of zoledronic acid (ZA) on MMP activity analyzed by gelatin zymography. MMP-2 and MMP-9 activities were evidenced at the corresponding molecular weight. Subconfluent A-673 and TC-71 human ES cell lines were cultured in the presence or absence of zoledronic acid at increasing concentrations (5 to 100 μM) for the last 24 h of culture. The supernatant was then harvested and the same volume submitted to electrophoresis in a gel containing gelatin (see Methods section).

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