Figure 5
From: Presence of intratumoral platelets is associated with tumor vessel structure and metastasis
Platelets changed intratumoral levels of angiogenic factors. (A), (B) Western blot analysis of Angiopoietin-1, 2 expression in tumors from control and PLT-depleted mice. Quantification of western blot analysis for each protein (normalized to β-actin). (C) Microdialysis was used to sample extracellular proteins in vivo. Extracellular VEGF level was measured by ELISA as described in Materials and Methods. The results are expressed as the mean ± SEM. * p < 0.05. (n = 6 for each group).