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Table 3 Cox hazards regression analysis of the clinicopathological factors

From: Cyr61 Expression is associated with prognosis in patients with colorectal cancer

Clinicopathological factors Univariate analysis Multivariate analysis
Hazard ratio (95% CI) P Hazard ratio (95% CI) P
Age 1.01 (0.99–1.03) 0.514 1.00 (0.98–1.03) 0.858
Sex (0 = male, 1 = female) 1.03 (0.60–1.77) 0.917 1.20 (0.66–2.20) 0.548
pT stage   
1 1.00   1.00  
2 1.09 (0.24–5.03) 0.916 0.93 (0.18–4.86) 0.927
3 1.13 (0.27–4.70) 0.864 0.99 (0.19–4.88) 0.967
4 3.44 (0.68–17.78) 0.140 2.15 (0.34–13.86) 0.419
pN stage   
0 1.00   1.00  
1 1.83 (0.99–3.40) 0.056 2.02 (1.04–3.94) 0.038
2 2.90 (1.44–5.83) 0.003 2.53 (1.20–5.32) 0.015
Venous invasion 1.00 (0.45–2.21) 0.991 0.67 (0.23–1.96) 0.463
Lymphatic invasion 1.84 (0.98–3.44) 0.057 1.97 (0.79–4.90) 0.143
Differentiation   
Well 1.00   1.00  
Moderate 0.70 (0.36–1.40) 0.298 0.61 (0.28–1.30) 0.198
Poor 0.86 (0.24–3.08) 0.817 0.75 (0.18–3.09) 0.692
Cyr61 Expression   
Negative 1.00   1.00  
Negative to mild expression 0.89 (0.48–1.67) 0.721 0.86 (0.44–1.70) 0.662
Moderate to severe expression 2.56 (1.29–5.08) 0.007 2.31 (1.09–4.89) 0.029
  1. CI, confidence interval.