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Table 3 Cox hazards regression analysis of the clinicopathological factors

From: Cyr61 Expression is associated with prognosis in patients with colorectal cancer

Clinicopathological factors

Univariate analysis

Multivariate analysis

Hazard ratio (95% CI)

P

Hazard ratio (95% CI)

P

Age

1.01 (0.99–1.03)

0.514

1.00 (0.98–1.03)

0.858

Sex (0 = male, 1 = female)

1.03 (0.60–1.77)

0.917

1.20 (0.66–2.20)

0.548

pT stage

  

 1

1.00

 

1.00

 

 2

1.09 (0.24–5.03)

0.916

0.93 (0.18–4.86)

0.927

 3

1.13 (0.27–4.70)

0.864

0.99 (0.19–4.88)

0.967

 4

3.44 (0.68–17.78)

0.140

2.15 (0.34–13.86)

0.419

pN stage

  

 0

1.00

 

1.00

 

 1

1.83 (0.99–3.40)

0.056

2.02 (1.04–3.94)

0.038

 2

2.90 (1.44–5.83)

0.003

2.53 (1.20–5.32)

0.015

Venous invasion

1.00 (0.45–2.21)

0.991

0.67 (0.23–1.96)

0.463

Lymphatic invasion

1.84 (0.98–3.44)

0.057

1.97 (0.79–4.90)

0.143

Differentiation

  

 Well

1.00

 

1.00

 

 Moderate

0.70 (0.36–1.40)

0.298

0.61 (0.28–1.30)

0.198

 Poor

0.86 (0.24–3.08)

0.817

0.75 (0.18–3.09)

0.692

Cyr61 Expression

  

 Negative

1.00

 

1.00

 

 Negative to mild expression

0.89 (0.48–1.67)

0.721

0.86 (0.44–1.70)

0.662

 Moderate to severe expression

2.56 (1.29–5.08)

0.007

2.31 (1.09–4.89)

0.029

  1. CI, confidence interval.