From: Cyr61 Expression is associated with prognosis in patients with colorectal cancer
Clinicopathological factors | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
Hazard ratio (95% CI) | P | Hazard ratio (95% CI) | P | |
Age | 1.01 (0.99–1.03) | 0.514 | 1.00 (0.98–1.03) | 0.858 |
Sex (0 = male, 1 = female) | 1.03 (0.60–1.77) | 0.917 | 1.20 (0.66–2.20) | 0.548 |
pT stage | Â | Â | ||
 1 | 1.00 |  | 1.00 |  |
 2 | 1.09 (0.24–5.03) | 0.916 | 0.93 (0.18–4.86) | 0.927 |
 3 | 1.13 (0.27–4.70) | 0.864 | 0.99 (0.19–4.88) | 0.967 |
 4 | 3.44 (0.68–17.78) | 0.140 | 2.15 (0.34–13.86) | 0.419 |
pN stage | Â | Â | ||
 0 | 1.00 |  | 1.00 |  |
 1 | 1.83 (0.99–3.40) | 0.056 | 2.02 (1.04–3.94) | 0.038 |
 2 | 2.90 (1.44–5.83) | 0.003 | 2.53 (1.20–5.32) | 0.015 |
Venous invasion | 1.00 (0.45–2.21) | 0.991 | 0.67 (0.23–1.96) | 0.463 |
Lymphatic invasion | 1.84 (0.98–3.44) | 0.057 | 1.97 (0.79–4.90) | 0.143 |
Differentiation | Â | Â | ||
 Well | 1.00 |  | 1.00 |  |
 Moderate | 0.70 (0.36–1.40) | 0.298 | 0.61 (0.28–1.30) | 0.198 |
 Poor | 0.86 (0.24–3.08) | 0.817 | 0.75 (0.18–3.09) | 0.692 |
Cyr61 Expression | Â | Â | ||
 Negative | 1.00 |  | 1.00 |  |
 Negative to mild expression | 0.89 (0.48–1.67) | 0.721 | 0.86 (0.44–1.70) | 0.662 |
 Moderate to severe expression | 2.56 (1.29–5.08) | 0.007 | 2.31 (1.09–4.89) | 0.029 |