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Table 3 Cox regression models of factors associated with breast cancer survival for NSW women 2001–2007 (n = 26762)

From: Increasing rates of surgical treatment and preventing comorbidities may increase breast cancer survival for Aboriginal women

 

Unadjusted model

Multivariable model

 

Hazard ratio (95% CI)

p-value

Hazard ratio (95% CI)

p-value

Aboriginal

1.69

1.22-2.25

0.002

1.30

0.94-1.75

0.105

Age at diagnosis

  

<0.001

  

<0.001

  20-49

1.16

1.03-1.31

 

1.03

0.91-1.16

 

  50-69

1.00

  

1.00

  

  60-69

0.91

0.80-1.04

 

0.90

0.79-1.02

 

  70-79

1.71

1.51-1.93

 

1.52

1.35-1.72

 

  80+

3.52

3.12-3.97

 

2.27

1.99-2.59

 

Year of diagnosis

0.97

0.95-1.00

0.018

0.96

0.94-0.98

<0.001

Spread of disease

  

<0.001

  

<0.001

  Localised

1.00

  

1.00

  

  Regional

3.90

3.50-4.35

 

3.63

3.25-4.06

 

  Distant

24.46

21.76-27.53

 

11.85

10.40-13.50

 

  Unknown

5.40

4.64-6.29

 

2.41

2.05-2.83

 

Comorbiditiesa

      

  Diabetes

1.52

1.33-1.72

<0.001

1.09

0.96-1.24

0.187

  Cardiovascular disease

3.27

2.86-3.72

<0.001

1.18

1.02-1.37

0.030

  Chronic pulmonary disease

1.63

1.37-1.92

<0.001

1.13

0.95-1.34

0.166

  Other comorbidities

3.95

3.47-4.48

<0.001

1.60

1.38-1.84

<0.001

Surgical treatment

  

<0.001

  

<0.001

  No surgical treatment

1.00

  

1.00

  

  Local excision/Lumpectomy only

0.06

0.06-0.07

 

0.17

0.15-0.19

 

  Mastectomyb

0.17

0.15-0.18

 

0.31

0.28-0.34

 

Socioeconomic disadvantage

  

<0.001

  

0.018

  Least disadvantaged

1.00

  

1.00

  

  Second least disadvantaged

1.14

1.00-1.29

 

1.09

0.96-1.24

 

  Third least disadvantaged

1.31

1.15-1.49

 

1.17

1.03-1.34

 

  Second most disadvantaged

1.33

1.17-1.50

 

1.25

1.09-1.42

 

  Most disadvantaged

1.35

1.19-1.52

 

1.19

1.02-1.38

 

Place of residence

  

0.014

  

0.703

  Major cities

1.00

  

1.00

  

  Inner regional

1.11

1.01-1.22

 

1.03

0.92-1.15

 

  Ruralb

1.20

1.02-1.40

 

0.96

0.80-1.15

 
  1. aPresence compared with the absence for each comorbidity.
  2. bIncludes mastectomy with or without local excision/lumpectomy.