Figure 2

Summary of NF к B centered NKX3.1 target gene signatures from in silico (left panel) and from the meta-analysis of in vivo data (right panel). Experimentally validated human genes and their orthologues in mouse are highlighted in yellow. Secondary nodes representing genes with four or more functional connections are stemming from the central regulatory node (green boxes). Nodes with four or more functional connections are outlined by red. Connected genes are marked with white background color.