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Table 2 Results of treatment

From: Primary localized rectal/pararectal gastrointestinal stromal tumors: results of surgical and multimodal therapy from the French Sarcoma group

Characteristic

n = 41 localized tumors

Quality of surgery

 

 Resection

 

  R0

22 (53%)

  R1

13 (32%)

  R2

4 (10%)

  Tumor rupture

 

  Yes

9 (22%)

  No

29 (70%)

 Primary surgery/Post imatinib surgery

29/12

 Post-operative complications

7 (17%)

  Anastomotic leakage of coloanal anastomosis

2

  Small bowel fistula with death

1

  Pelvic peritonitis

1

  Pararectal abscess and anorectal fistula

1

  Occlusion

1

  Fever

1

Imatinib (IM) therapy group (400 mg/day)

16 (37.5%)

 Preoperative IM

12 (30%)

 No neoadjuvant IM group (immediate surgery)

29 (70%)

 Post operative IM

11 (27%)

  from « neoadjuvant group »

7

  from « immediate surgery group »

4

 Median duration preoperative IM (month)

7 (2-12)

 Median duration post operative IM (month)

7 (2-41)

Efficacy of preoperative IM therapy

12

  Partial response

8

  Complete response

1

  Stable disease/minor response

3