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Table 2 Pathological conditions associated with MCT1 and MCT4 expression

From: Tumor-stroma metabolic relationship based on lactate shuttle can sustain prostate cancer progression

Tissue

Expression/total number (%)

P-value#

 

Null

Low*

High**

 
  

MCT1

  

BPH

48% (29/60)

47% (28/60)

5% (3/60)

0.07

PCa

31% (25/80)

56% (45/80)

13% (10/80)

  

MCT4

  

BPH

92% (55/60)

5% (3/60)

3% (2/60)

<0.01

PCa

35% (28/80)

45% (36/80)

20% (16/80)

  

Stromal MCT4

  

BPH

50% (30/60)

45% (27/60)

2% (3/60)

<0.01

PCa

25% (20780)

61% (49/80)

14% (11/80)

 
  1. *Low (grade <6 immunostaining); ** high (grade ≥6 immunostaining); # χ2 test.