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Table 5 Summary estimates of the odds ratio (OR) for the associations of High Ki-67 expression and clinical-pathological features of lymphoma

From: Ki-67 is a valuable prognostic predictor of lymphoma but its utility varies in lymphoma subtypes: evidence from a systematic meta-analysis

 

Heterogeneity

Clinicopathological features

Nuber of studies

Nuber of patients

Pooled OR(95% CI)

P value

I2(%)

P value

Performance status (0–1 vs.2-5)

7

643

1.082(0.654-1.793)

0.758

31.7

0.186

Elevated LDH (normal vs. elevated)

10

884

0.914(0.673-1.241)

0.564

36.6

0.115

IPI score (0–2 vs.3-5)

7

611

0.963(0.667-1.39)

0.84

0

0.53

Tumor stage (I-II vs. III-IV)

9

845

1.089(0.79-1.501)

0.604

37.4

0.119

B symptom (no vs. yes)

10

944

0.851(0.557-1.3)

0.455

45

0.059

Extranodal site (no vs. yes)

9

758

1.017(0.674-1.534)

0.937

20.7

0.259