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Figure 4 | BMC Cancer

Figure 4

From: Akt inhibitor MK-2206 promotes anti-tumor activity and cell death by modulation of AIF and Ezrin in colorectal cancer

Figure 4

MK-2206 inhibits Akt signaling in vivo : A) IHC images showing a reduction in pAkt at Ser473. B) Relative quantification was performed, followed by statistical analysis to determine the decrease in phosphorylation of Akt at Ser473 on treatment with MK-2206. C) Western blot analysis to confirm the loss of pAkt at Ser473 and Thr 308 in treated animals. (* = P < 0.01 and ** = P < 0.001).

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BMC Cancer

ISSN: 1471-2407

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