Skip to main content

Table 3 Relationships between microsatellite analysis (DXS1047), XCI pattern, and clinical parameters

From: Androgen receptor CAG repeats, non-random X chromosome inactivation, and loss of heterozygosity at Xq25 in relation to breast cancer risk

Patients in whom no LOH was found at the DXS1047 microsatellite marker Patients in whom LOH was found at the DXS1047 microsatellite marker  
  No. %   No. % Pvaluee
R a 14/24 58.3% R a 10/20 50% 0.80
N b 10/24 41.7% N b 10/20 50%
Tumour Grade 1.2 22/28 78.6% Tumour Grade 1.2 15/25 60% 0.24
Tumour Grade 3 6/28 21.4% Tumour Grade 3 10/25 40%
LNMc+ 17/28 60.7% LNMc+ 12/28 42.9% 0.28
LNMd 11/28 39.2% LNMd 14/28 57.1%
Tumour Size (<3 cm) 11/28 39.3% Tumour Size (<3 cm) 14/26 53.8% 0.28
Tumour Size (>3 cm) 17/28 60.7% Tumour Size (>3 cm) 12/26 46.2%
  1. This table presents the relationships between microsatellite analysis (DXS1047), XCI pattern, and clinical parameters (including tumour grade, lymph node metastases, and tumour size).
  2. a. N: The XCI pattern in the tumour tissues was non-random.
  3. b. R: The XCI pattern in the tumour tissues was random.
  4. c. LNM+: Patients with lymph node metastases.
  5. d. LNM–: Patients without lymph node metastases.
  6. e. Chi-square test and Fisher’s exact probability test.