Androgen receptor CAG repeats, non-random X chromosome inactivation, and loss of heterozygosity at Xq25 in relation to breast cancer risk

Table 2 Relationships between microsatellite analysis, XCI pattern, and clinical parameters

Patients in which no LOH was observed at any microsatellite markers			Patients in which LOH was observed at one or more microsatellite markers
	No.	%		No.	%	Pvalue^e
R ^a	11/15	73.3%	R ^a	20/36	55.56%	0.35
N ^b	4/15	26.7%	N ^b	16/36	44.44%	0.35
Tumour Grade 1.2	15/19	78.9%	Tumour Grade 1.2	30/44	68.18%	0.55
Tumour Grade 3	4/19	21.1%	Tumour Grade 3	14/44	31.82%	0.55
LNM^c+	13/19	68.4%	LNM^c+	22/45	48.89%	0.25
LNM^d–	6/19	31.6%	LNM^d–	23/45	51.11%	0.25
Tumour Size (<3 cm)	8/17	47.1%	Tumour Size (<3 cm)	22/45	48.89%	0.88
Tumour Size (>3 cm)	9/17	52.9%	Tumour Size (>3 cm)	23/45	51.11%	0.88

This table presents the relationships between microsatellite analysis, XCI pattern, and clinical parameters (including tumour grade, lymph node metastases, and tumour size).
a. N: The XCI pattern in the tumour tissues was non-random.
b. R: The XCI pattern in the tumour tissues was random.
c. LNM+: Patients with lymph node metastases.
d. LNM–: Patients without lymph node metastases.
e. Chi-square test and Fisher’s exact probability test.

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