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Table 1 Patient characteristics and their variables as predictors for disease-spesific survival in 335 NSCLC patients (univariate analyses; log-rank test)

From: Stage and tissue-specific prognostic impact of miR-182 in NSCLC

Characteristics Patients Median survival 5-year survival P
  n (%) months %  
Age      
  ≤ 65 years 156 (47) 98 55 0.42
  >65 years 179 (53) NR 60  
Sex      
  Female 82 (24) 190 64 0.22
  Male 253 (76) 98 56  
Smoking      
  Never 15 (5) 19 43 0.26
  Current 215 (64) NR 60  
  Former 105 (31) 84 55  
Performance status      
  PS 0 197 (59) NR 63 0.016
  PS 1 120 (36) 64 52  
  PS 2 18 (5) 25 33  
Weight loss      
  < 10% 303 (90) 190 58 0.76
  > 10% 32 (10) 98 57  
Histology      
  SCC 191 (57) NR 66 0.028
  Adenocarcinoma 113 (34) 54 46  
  LCC 31 (9) 98 56  
Differentiation      
  Poor 138 (41) 47 47 < 0.001
  Moderate 144 (43) 190 65  
  Well 53 (16) NR 68  
Surgical procedure      
  Lobectomy + wedge* 243 (73) 190 62 0.007
  Pneumonectomy 92 (27) 37 47  
Pathological stage      
  I 157 (47) NR 61 < 0.001
  II 136 (40) 62 51  
  IIIa 42 (13) 17 23  
Tumor status      
  1 85 (25) 190 75 < 0.001
  2 188 (56) 84 57  
  3 62 (19) 25 36  
Nodal status      
  0 232 (69) NR 67 < 0.001
  1 76 (23) 35 43  
  2 27 (8) 18 18  
Surgical margins      
  Free 307 (92) 190 59 0.37
  Not free 28 (8) 47 48  
Vascular infiltration      
  No 284 (85) 190 62 0.001
  Yes 51 (15) 27 33  
  1. Statistically significant results in bold font.
  2. *Wedge, n = 10.
  3. Abbreviations: NR not reached, PS performance status, SCC squamos cell carcinoma, LCC large-cell carcinoma. Adenocarcinoma including cases with bronchioloalveolar carcinoma.