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Table 1 Clinicopathological characteristics of patients and univariate analysis for OS after SCR

From: Salvage cytoreductive surgery for patients with recurrent endometrial cancer: a retrospective study

  Cases Deaths Median OS (months) UVaanalysis (Pvalue)
Age at second surgery     0.549
  ≤56 years 38 15 60  
  >56 years 37 15 39  
ECOG performance status at first surgery     0.352
  0 6 1 48.00  
  1 62 25 62.124  
  2 7 4 34.00  
Stage at first surgery (FIGO 2009)     0.760
  Stage I-II 58 22 65.675  
  Stage III-IV 17 8 45.159  
Pathological subtype     0.180
  Endometrioid 65 28 57.753  
  Nonendometrioid 10 2 52.10  
Histological grade     
  I 14 4 67.921 0.068
  II 39 15 68.006 0.040*
  III 22 11 44.819 Reference
Postoperative therapy after first surgery     0.309
  Chemotherapy 33 14 53.51  
  Radiotherapy 5 2 36  
  CT+RT 6 1 72  
  Hormonal therapy 4 1 114  
  No 27 12 36.196  
Symptoms at recurrence     0.723
  Nonsymptomatic 30 13 54  
  Symptomatic 45 17 65  
CA125 at recurrence     0.108
  ≤ 35 U/ml 25 7 69.650  
  >35 U/ml 35 18 35.733  
  Not available 15 5 77.548  
Recurrence detection of nonsymptomatic     0.134
  Imaging or CA-125 17 8 44.83  
  Physical examination 13 4 96  
PFI     0.032*
  ≤18 months 40 19 34.963  
  >18 months 35 11 76.078  
Largest size of recurrence     0.008*
  ≤ 6 cm 36 10 79.027  
  > 6 cm 39 20 35.918  
Multiplicity of recurrence     0.144
  Solitary 35 12 73.219  
  Multiple 40 18 37.295  
Site of recurrence     0.056
  Pelvis b and/or introabdomonal 63 23 66.186  
  Retroperitoneal 12 7 30.380  
Ascites     0.048*
  None 67 26 64.678  
  Yes 8 4 17.171  
ECOG performance status before SCR     0.311
  0 30 13 53.28  
  1 26 9 109.31  
  2 14 5 72.0  
  3 5 3 14.4  
Residual disease after SCR     
  None 43 12 76.462 0.000*
  0.1~1 cm 15 6 43.825 0.001*
  1~2 cm 6 4 30.833 0.207
  >2 cm 11 8 12.778 Reference
Postoperative therapy after SCR     
  Chemotherapy 48 22 40.192 Reference
  Radiotherapy 6 1 114.0 0.045*
  CT+RT 8 3 42.0 0.764
  No 13 4 72.0 0.615
  1. Note. a, UV, univariate; b, pelvis: including inguinal and vaginal; CT: chemotherapy; RT: radiotherapy; *P <0.05.