Figure 1

Transcript abundance of insulin receptor isoforms in LUAD and LUSC profiled by TCGA RNA-seq data. A) Log2-transformed and normalized read count of IR-A and IR-B receptor isoforms in LUAD (n = 355), LUSC (n = 259) and adjacent normal tissue (n = 92) and B) the corresponding distribution of log2-transformed IR-A/IR-B mRNA ratio. Asterisks indicate statistically significant differences (* = P < 0.05; ** = P < 0.01; *** = P < 0.001).