Probe combination | Probe parameters | Cut-off 1 | Cut-off 2 | Cut-off 3 | Cut-off 4 | Sensitivity | Specificity | AUC |
---|---|---|---|---|---|---|---|---|
Probe combination 1 | PTEN%loss, CEP7%abnormal, MYC%gain, CEP8%abnormal | 33 PTEN% loss | 28 CEP7% abnormal | 35 MYC% gain | 34 CEP8% abnormal | 88.20% | 84.60% | 0.917 |
Probe combination 2 | PTEN/CEP10%loss, CEP7%abnormal, MYC%gain | 35 PTEN/CEP10% loss | 25 CEP7% abnormal | 35 MYC% gain | NA | 82.40% | 80.80% | 0.911 |
Probe combination 3 | PTEN/CEP10%loss, CEP7%abnormal, CEP8%abnormal | 35 PTEN/CEP10% loss | 25 CEP7% abnormal | 34 CEP8% abnormal | NA | 88.20% | 80.80% | 0.938 |
Probe combination 4 | PTEN/CEP10%loss, MYC%gain, CEP8gain | 35 PTEN/CEP10% loss | 5 MYC% gain | 35 CEP8% gain | NA | 64.70% | 88.50% | 0.834 |