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Table 7 Intracellular chemokine expression after xenotransplantation

From: Intracellular coexpression of CXC- and CC– chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation

  CXCL9 CXCL10 CXCL11 CXCL12 CCL19 CCL21 CCL27 CCL28
  % MFI % MFI % MFI % MFI % MFI % MFI % MFI % MFI
WM-115 28.31 2.06 0.46 1.12 2.66 1.24 81.77 3.96 98.79 20.00 15.55 1.65 94.06 4.89 ns 0.94
WM-115-X ns 1.10 ns 0.90 ns 0.96 0.30 0.94 50.38 3.80 ns 1.05 22.39 1.62 ns 0.97
WM-115-CX 50.39 5.36 4.33 2.54 15.24 5.25 79.83 5.08 98.64 36.76 14.46 4.24 98.17 13.36 3.51 2.98
WM-266 71.84 4.57 15.19 1.74 46.26 3.24 98.24 9.56 98.58 30.17 60.21 3.71 98.50 11.38 1.14 1.25
WM-266-X 2.12 1.46 2.53 1.28 22.73 1.93 3.81 1.42 81.95 10.43 2.38 1.33 54.41 3.39 1.25 1.19
WM-266-CX 67.84 7.02 3.72 1.41 37.75 4.98 95.52 14.66 98.10 43.82 50.06 4.00 97.12 12.36 0.29 0.97
  1. Mean percentage (%) and mean fluorescence index (MFI; calculated as the ratio between the mean fluorescence of samples stained with the mAb anti-receptor and correspondent isotypic control) of cells which significantly expressed (p < 0.05) chemokine ligands intracellularly. WM-115 and WM-266 represent the mean values of the original cell lines; WM-115-X and WM-266-X represent the mean values of the different xenografts; WM-115-CX and WM-266-CX represent the mean values of the different cell lines obtained after culturing the xenografts.