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Table 4 Intracellular expression of chemokine ligands

From: Intracellular coexpression of CXC- and CC– chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation

Origin Cell line CXCL9 CXCL10 CXCL11 CXCL12 CCL19 CCL21 CCL27 CCL28
   % MFI % MFI % MFI % MFI % MFI % MFI % MFI % MFI
P IPC-298 95.39 3.69 0.93 1.11 7.00 1.36 97.93 5.34 99.02 16.86 53.98 1.94 98.71 7.39 ns ns
P Mel-Juso 93.22 10.88 ns ns 12.90 2.10 89.57 5.80 99.04 70.62 6.12 1.60 98.75 17.36 ns ns
P Mel-HO 96.59 8.39 7.32 1.32 65.87 5.83 97.86 8.12 98.62 60.07 82.62 3.72 98.65 23.48 ns ns
P IGR-39 14.05 1.52 ns ns 10.49 1.37 95.86 3.89 98.76 16.71 23.50 1.54 98.58 5.21 ns ns
P WM-115 28.31 2.06 0.46 1.12 2.66 1.24 81.77 3.96 98.79 20.00 15.55 1.65 94.06 4.89 ns ns
M A-375 84.56 6.18 0.42 1.07 88.71 7.46 10.89 1.67 92.34 71.31 32.60 3.42 89.92 25.21 1.14 1.29
M MeWo 45.53 5.28 1.46 1.44 46.10 8.72 24.41 2.15 50.06 34.71 23.62 3.96 37.85 10.86 1.74 1.86
M SK-Mel28 67.63 3.06 2.01 1.18 82.59 5.72 71.82 3.09 86.62 44.41 28.42 1.96 86.34 14.37 ns ns
M Malme-3 M 50.32 3.45 ns ns 71.62 3.45 77.48 3.37 98.02 34.57 5.45 1.70 97.90 11.06 ns ns
M SK-Mel 2 81.72 3.18 ns ns 94.63 5.53 95.94 8.46 98.34 36.70 22.45 1.86 97.47 13.02 ns ns
M WM-266-4 71.84 4.57 15.19 1.74 46.26 3.24 98.24 9.56 98.58 30.17 60.21 3.71 98.50 11.38 1.14 1.25
M IGR-37 87.92 5.06 ns ns 36.32 1.88 92.76 3.78 98.83 47.66 38.71 2.44 98.96 21.35 ns ns
M Mel-RC08 49.96 3.29 ns ns 80.84 6.87 16.64 1.68 86.38 55.25 22.94 2.19 82.77 15.33 1.56 1.22
P Hut-78 1.90 1.69 ns ns ns ns ns ns 65.99 11.71 ns ns 39.11 3.81 ns ns
  1. For each cell line (Origin; P: primary tumor, M: metastasis) mean percentage (%) and mean fluorescence index (MFI; calculated as the ratio between the mean fluorescence of the samples stained with the mAb anti-receptor and their correspondent isotypic control) of cells which significantly expressed (p < 0.05) chemokine ligands intracellularly are shown (ns: not significant expression).