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Table 3 Intracellular expression of chemokine receptors

From: Intracellular coexpression of CXC- and CC– chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation

Origin Cell line CXCR3 CXCR4 CXCR7 CCR7 CCR10
   % MFI % MFI % MFI % MFI % MFI
P IPC-298 99.45 7.34 99.41 6.29 21.26 1.48 58.30 1.92 45.67 1.86
P Mel-Juso 53.74 3.27 62.50 4.16 3.58 1.18 39.58 2.51 18.64 1.78
P Mel-HO 96.71 5.28 98.99 7.82 53.07 2.21 82.49 3.13 56.36 2.26
P IGR-39 95.73 3.73 95.76 4.04 81.82 2.59 87.87 2.43 37.51 1.70
P WM-115 88.59 5.40 92.45 3.95 4.97 1.57 20.16 1.70 13.67 1.57
M A-375 43.61 2.51 94.44 14.10 63.20 3.45 12.70 1.59 45.45 2.89
M MeWo 25.02 2.21 80.60 5.98 80.65 6.59 2.58 1.32 61.27 3.53
M SK-Mel28 56.56 2.43 93.22 8.63 73.86 5.02 1.20 1.20 65.81 2.59
M Malme-3 M 64.99 2.07 92.84 2.66 97.78 5.66 64.86 1.99 71.88 2.37
M SK-Mel 2 96.43 6.92 98.33 15.73 33.52 2.04 78.23 2.08 96.34 4.68
M WM-266-4 74.08 2.22 96.26 3.39 21.53 1.68 40.16 1.69 24.00 1.63
M IGR-37 97.88 4.25 97.85 4.53 43.84 1.89 67.83 2.03 56.29 1.89
M Mel-RC08 45.79 2.69 95.02 7.33 72.05 3.99 9.14 1.61 60.81 2.84
P Hut-78 82.05 2.93 95.95 4.62 19.75 1.95 13.53 1.68 88.40 4.08
  1. For each cell line (Origin; P: primary tumor, M: metastasis) mean percentage (%) and mean fluorescence index (MFI; calculated as the ratio between the mean fluorescence of the samples stained with the mAb anti-receptor and their correspondent isotypic control) of cells which significantly expressed (p < 0.05) chemokine receptors intracellularly are shown (ns: not significant expression).