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Table 3 Intracellular expression of chemokine receptors

From: Intracellular coexpression of CXC- and CC– chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation

Origin

Cell line

CXCR3

CXCR4

CXCR7

CCR7

CCR10

  

%

MFI

%

MFI

%

MFI

%

MFI

%

MFI

P

IPC-298

99.45

7.34

99.41

6.29

21.26

1.48

58.30

1.92

45.67

1.86

P

Mel-Juso

53.74

3.27

62.50

4.16

3.58

1.18

39.58

2.51

18.64

1.78

P

Mel-HO

96.71

5.28

98.99

7.82

53.07

2.21

82.49

3.13

56.36

2.26

P

IGR-39

95.73

3.73

95.76

4.04

81.82

2.59

87.87

2.43

37.51

1.70

P

WM-115

88.59

5.40

92.45

3.95

4.97

1.57

20.16

1.70

13.67

1.57

M

A-375

43.61

2.51

94.44

14.10

63.20

3.45

12.70

1.59

45.45

2.89

M

MeWo

25.02

2.21

80.60

5.98

80.65

6.59

2.58

1.32

61.27

3.53

M

SK-Mel28

56.56

2.43

93.22

8.63

73.86

5.02

1.20

1.20

65.81

2.59

M

Malme-3 M

64.99

2.07

92.84

2.66

97.78

5.66

64.86

1.99

71.88

2.37

M

SK-Mel 2

96.43

6.92

98.33

15.73

33.52

2.04

78.23

2.08

96.34

4.68

M

WM-266-4

74.08

2.22

96.26

3.39

21.53

1.68

40.16

1.69

24.00

1.63

M

IGR-37

97.88

4.25

97.85

4.53

43.84

1.89

67.83

2.03

56.29

1.89

M

Mel-RC08

45.79

2.69

95.02

7.33

72.05

3.99

9.14

1.61

60.81

2.84

P

Hut-78

82.05

2.93

95.95

4.62

19.75

1.95

13.53

1.68

88.40

4.08

  1. For each cell line (Origin; P: primary tumor, M: metastasis) mean percentage (%) and mean fluorescence index (MFI; calculated as the ratio between the mean fluorescence of the samples stained with the mAb anti-receptor and their correspondent isotypic control) of cells which significantly expressed (p < 0.05) chemokine receptors intracellularly are shown (ns: not significant expression).