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Table 2 Surface expression of chemokine receptors

From: Intracellular coexpression of CXC- and CC– chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation

Origin Cell line CXCR3 CXCR4 CXCR7 CCR7 CCR10
   % MFI % MFI % MFI % MFI % MFI
P IPC-298 0.16 3.10 ns - ns - ns - 0.23 11.37
P Mel-Juso ns - ns - 0.43 27.70 ns - 0.43 12.74
P Mel-HO 0.07 4.83 ns - 0.36 4.91 ns - ns -
P IGR-39 0.83 8.31 ns - 1.59 7.09 ns - 1.79 4.05
P WM-115 0.15 5.91 ns - ns - ns - 0.11 5.09
M A-375 ns - ns - ns - ns - ns -
M MeWo ns - ns - ns - ns - ns -
M SK-Mel28 ns - ns - ns - ns - ns -
M Malme-3 M ns - ns - ns - ns - ns -
M SK-Mel 2 0.44 3.16 ns - 0.35 10.34 ns - 0.35 3.84
M WM-266-4 ns - ns - ns - ns - ns -
M IGR-37 0.13 3.47 ns - 0.22 14.76 ns - ns -
M Mel-RC08 ns - ns - ns - ns - ns -
P Hut-78 63.07 3.37 5.90 6.91 ns - 3.36 7.66 1.23 8.36
  1. For each cell line (Origin; P: primary tumor, M: metastasis) mean percentage (%) and mean fluorescence index (MFI; calculated as the ratio between the mean fluorescence of the positive population in the samples stained with the mAb anti-receptor and their correspondent isotypic control) of cells which significantly expressed (p < 0.05) chemokine receptors at the cell surface are shown (ns: not significant expression).