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Table 2 Surface expression of chemokine receptors

From: Intracellular coexpression of CXC- and CC– chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation

Origin

Cell line

CXCR3

CXCR4

CXCR7

CCR7

CCR10

  

%

MFI

%

MFI

%

MFI

%

MFI

%

MFI

P

IPC-298

0.16

3.10

ns

-

ns

-

ns

-

0.23

11.37

P

Mel-Juso

ns

-

ns

-

0.43

27.70

ns

-

0.43

12.74

P

Mel-HO

0.07

4.83

ns

-

0.36

4.91

ns

-

ns

-

P

IGR-39

0.83

8.31

ns

-

1.59

7.09

ns

-

1.79

4.05

P

WM-115

0.15

5.91

ns

-

ns

-

ns

-

0.11

5.09

M

A-375

ns

-

ns

-

ns

-

ns

-

ns

-

M

MeWo

ns

-

ns

-

ns

-

ns

-

ns

-

M

SK-Mel28

ns

-

ns

-

ns

-

ns

-

ns

-

M

Malme-3 M

ns

-

ns

-

ns

-

ns

-

ns

-

M

SK-Mel 2

0.44

3.16

ns

-

0.35

10.34

ns

-

0.35

3.84

M

WM-266-4

ns

-

ns

-

ns

-

ns

-

ns

-

M

IGR-37

0.13

3.47

ns

-

0.22

14.76

ns

-

ns

-

M

Mel-RC08

ns

-

ns

-

ns

-

ns

-

ns

-

P

Hut-78

63.07

3.37

5.90

6.91

ns

-

3.36

7.66

1.23

8.36

  1. For each cell line (Origin; P: primary tumor, M: metastasis) mean percentage (%) and mean fluorescence index (MFI; calculated as the ratio between the mean fluorescence of the positive population in the samples stained with the mAb anti-receptor and their correspondent isotypic control) of cells which significantly expressed (p < 0.05) chemokine receptors at the cell surface are shown (ns: not significant expression).
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BMC Cancer

ISSN: 1471-2407

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