Table 1 Selected characteristics of women participating in the NJ ovarian cancer study
Cases (n=205) | Controls (n=390) | Age-adjusted | |||
|---|---|---|---|---|---|
n (%) | n (%) | OR (95% CI) | |||
Education | |||||
High school or less | 61 | (29.8) | 132 | (33.9) | 1.00 (Ref) |
College | 93 | (45.4) | 159 | (40.8) | 0.90 (0.59-1.38) |
Graduate school | 51 | (24.9) | 99 | (25.4) | 0.76 (0.47-1.24) |
Race/ethnicity | |||||
White | 179 | (87.3) | 343 | (88.4) | 1.00 (Ref) |
Black | 9 | (4.4) | 17 | (4.4) | 1.02 (0.42-2.44) |
Other | 8 | (3.9) | 17 | (4.4) | 0.82 (0.33-1.99) |
Hispanic (any race) | 9 | (4.4) | 11 | (2.8) | 1.13 (0.44-2.92) |
Parity* | |||||
0 – 1 | 97 | (47.3) | 92 | (23.6) | 1.00 (Ref) |
2 | 60 | (29.3) | 136 | (34.9) | 0.45 (0.29-0.69) |
≥3 | 48 | (23.4) | 162 | (41.5) | 0.42 (0.26-0.66) |
Oral contraceptive use | |||||
Never | 85 | (41.5) | 192 | (49.2) | 1.00 (Ref) |
Ever | 120 | (58.5) | 198 | (50.8) | 0.88 (0.61-1.28) |
Use of HRT | |||||
Never | 159 | (77.6) | 284 | (72.8) | 1.00 (Ref) |
Unopposed E only | 22 | (10.7) | 34 | (8.7) | 1.56 (0.86-2.83) |
Any combined HRT | 24 | (11.7) | 72 | (18.5) | 0.63 (0.38-1.06) |
Age at menarche | |||||
>13 | 41 | (20.1) | 98 | (25.2) | 0.81 (0.51-1.28) |
12-13 | 117 | (57.4) | 200 | (51.4) | 1.00 (Ref) |
≤11 | 46 | (22.6) | 91 | (23.4) | 0.75 (0.48-1.17) |
Menopause status* | |||||
Premenopausal | 71 | (34.6) | 49 | (12.6) | |
Postmenopausal | 134 | (65.4) | 341 | (87.4) | |
Age at menopause | |||||
<40 | 5 | (2.4) | 14 | (3.6) | 0.77 (0.26-2.31) |
41-54 | 86 | (42.0) | 239 | (61.3) | 1.00 (Ref) |
≥55 | 12 | (5.9) | 36 | (9.3) | 0.99 (0.48-2.02) |
Unknown | 31 | (15.1) | 52 | (13.3) | 1.52 (0.91-2.56) |
BMI | |||||
Normal (<25) | 91 | (44.4) | 180 | (46.5) | 1.00 (Ref) |
Overweight (25-29.9) | 54 | (26.3) | 122 | (31.5) | 1.07 (0.69-1.65) |
Obese (30-34.9) | 36 | (17.6) | 59 | (15.3) | 1.39 (0.83-2.32) |
Very obese (≥35) | 24 | (11.7) | 26 | (6.7) | 1.54 (0.82-2.89) |
Smoking status | |||||
Never | 108 | (52.7) | 203 | (52.1) | 1.00 (Ref) |
Past | 78 | (38.1) | 149 | (38.2) | 1.12 (0.76-1.64) |
Current | 19 | (9.3) | 38 | (9.7) | 0.87 (0.46-1.62) |
Tubal ligation | |||||
No | 175 | (85.4) | 314 | (80.5) | 1.00 (Ref) |
Yes | 30 | (14.6) | 76 | (19.5) | 0.59 (0.36-0.94) |
First degree relative with ovarian cancer | |||||
No | 195 | (95.1) | 376 | (96.4) | 1.00 (Ref) |
Yes | 10 | (4.9) | 14 | (3.6) | 1.32 (0.55-3.17) |