Table 1 Ovarian cancer patient demographics by ß-blocker use
From: Use of ß-blockers and mortality following ovarian cancer diagnosis: a population-based cohort study
Nonusers | Current users | Previous users | |
|---|---|---|---|
Number (%) | 6,166 (93.06) | 373 (5.63) | 87 (1.31) |
Age at diagnosis, years | |||
Median age (IQR) | 65 (56–75) | 66 (56–74) | 63 (55–73) |
20-40 | 213 (3.45) | 13 (3.49) | 1 (1.15) |
41-60 | 1,982 (32.14) | 118 (31.64) | 32 (36.78) |
61-80 | 3,188 (51.70) | 197 (52.82) | 42 (48.28) |
>80 | 783 (12.70) | 45 (12.06) | 12 (13.79) |
Stageb | |||
Localized | 1,848 (29.97) | 128 (34.32) | 28 (32.18) |
Regional | 1,931 (31.32) | 97 (26.01) | 16 (18.39) |
Distant | 1,920 (31.14) | 111 (29.76) | 33 (37.93) |
Unknown/missing | 467 (7.57) | 37 (9.92) | 10 (11.49) |
Comorbidity levelc | |||
Low | 4,127 (66.93) | 251 (67.29) | 58 (66.67) |
Moderate | 1,512 (24.52) | 88 (23.59) | 26 (29.89) |
High | 527 (8.55) | 34 (9.12) | 3 (3.45) |
Comorbidities | |||
Hypertension | 681 (11.04) | 45 (12.06) | 12 (13.79) |
Obesity | 71 (1.15) | 2 (0.54) | 0 (0.00) |
Atrial fibrillation/flutter | 222 (3.60) | 22 (5.90) | 8 (9.20) |
Angina pectoris | 257 (4.17) | 9 (2.41) | 0 (0.00) |
Myocardial infarction | 160 (2.59) | 10 (2.68) | 2 (2.30) |
Congestive heart failure | 183 (2.97) | 12 (3.22) | 4 (4.60) |
Esophageal varices | 5 (0.08) | 1 (0.27) | 0 (0.00) |
Tremor | 4 (0.06) | 0 (0.00) | 0 (0.00) |
Anxiety | 41 (0.66) | 1 (0.27) | 1 (1.15) |
Thyrotoxicosis | 182 (2.95) | 16 (4.29) | 5 (5.75) |
COPD | 227 (3.68) | 13 (3.49) | 4 (4.60) |
Migraines | 78 (1.27) | 3 (0.80) | 2 (2.30) |
Stroke | 223 (3.62) | 21 (5.63) | 4 (4.60) |
Chronic kidney disease | 81 (1.31) | 5 (1.34) | 3 (3.45) |
Hysterectomy | 358 (5.81) | 24 (6.43) | 7 (8.05) |
Tubal sterilization | 204 (3.31) | 11 (2.95) | 3 (3.45) |
Comedication use | |||
ACE-inhibitors | 351 (5.69) | 104 (27.88) | 30 (34.48) |
ARBs | 198 (3.21) | 60 (16.09) | 16 (18.39) |
Calcium channel blockers | 407 (6.60) | 112 (30.03) | 31 (35.63) |
Diuretics | 1,276 (20.69) | 234 (62.73) | 67 (77.01) |
Non-aspirin NSAIDs | 1,852 (30.04) | 220 (58.98) | 51 (58.62) |
Aspirin | 525 (8.51) | 157 (42.09) | 40 (45.98) |
Statins | 320 (5.19) | 111 (29.76) | 28 (32.18) |
HRT | 1,165 (18.89) | 126 (33.78) | 33 (37.93) |
Antipsychotics | 336 (5.45) | 41 (10.99) | 8 (9.20) |
Anxiolytics | 285 (4.62) | 22 (5.90) | 7 (8.05) |
Antidepressants | 816 (13.23) | 100 (26.81) | 24 (27.59) |