Figure 3
From: PRL-3 suppresses c-Fos and integrin α2 expression in ovarian cancer cells
Knock-down of endogenous PRL-3 leads to altered morphology of A2780 cells. Representative morphologic micrographs of vector control and A2780 PRL-3 KD cells after 48 h of growth in complete medium are shown. (A-C) Light micrographs showing normal morphology of vector control cells versus A2780 PRL-3 KD cells. (D-F) Transmission electron micrographs (TEM) showing normal morphology of vector control cells versus the flattened morphology of A2780 PRL-3 KD cells. (G-I) Hematoxylin and eosin staining demonstrating control cells versus the spread morphology of A2780 PRL-3 KD cells.