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Table 2 Association between methylation patterns of MLH1 and MGMT and histological subtypes

From: Correlation of MLH1 and MGMTexpression and promoter methylation with genomic instability in patients with thyroid carcinoma

Methylation status

PTC (n = 70)

FTC (n = 12)

Benign (n = 14)

N (%)

p*

N (%)

p*

N (%)

MLH1

Methylated

31/70 (44%)

0.242

4/12 (33%)

0.238

9/14 (64%)

Unmethylated

39/70 (56%)

8/12 (67%)

5/14 (36%)

MGMT

Methylated

45/70 (64%)

0.763

8/12 (67%)

0.701

8/14 (57%)

Unmethylated

25/70 (36%)

4/12 (33%)

6/14 (43%)

  1. *p values compared against benign group.