Table 3 Frequency distribution of all drug-related adverse events of at least grade 3
Dose level | ||||
|---|---|---|---|---|
Event | 1 | 2 | 3 | Total |
Number of patients | 4 (100%) | 13 (100%) | 7 (100%) | 24 (100%) |
Nausea | 1 (25%) | 2 (15%) | 3 (43%) | 6 (25%) |
Vomiting | 2 (50%) | 2 (15%) | 1 (14%) | 5 (21%) |
Dehydration | 1 (14%) | 1 (4%) | ||
Diarrhoea | 1 (14%) | 1 (4%) | ||
Dysphagia | 1 (8%) | 1 (4%) | ||
Heartburn/dyspepsia | 1 (14%) | 1 (4%) | ||
Fatigue | 1 (25%) | 1 (8%) | 3 (43%) | 5 (21%) |
Pain | 1 (14%) | 1 (4%) | ||
Platelets | 1 (8%) | 1 (14%) | 2 (8%) | |
Leukocytes | 1 (14%) | 1 (4%) | ||
Neutrophils | 1 (14%) | 1 (4%) | ||