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Table 1 Comparison of clinicopathological parameters of conventional UC, PUC and MPC urothelial carcinomas treated with radical cystectomy and adjuvant cisplatin based chemotherapy

From: Plasmacytoid variant of bladder cancer defines patients with poor prognosis if treated with cystectomy and adjuvant cisplatin-based chemotherapy

  Total UC PUC MPC P-Value*
Age      0.057**
Range 29-75 29-75 46-70 56-70  
Mean 60.9 61.0 57.9 62.3  
Median 61.7 61.9 59.3 60.8  
Gender 205 178 18 9 0.116
Female 45 (22%) 43 (24%) 2 (11%) 0 (0%)  
Male 160 (78%) 135 (76%) 16 (89%) 9 (100%)  
pT 205 178 18 9 0.168
pT1 5 (2,5%) 5 (3%) 0 (%) 0 (0%)  
pT2 22 (11%) 19 (11%) 3 (17%) 0 (0%)  
pT3 142 (69%) 125 (70%) 13 (72%) 4 (45%)  
pT4 36 (17.5%) 29 (16%) 2 (11%) 5 (55%)  
Grade (1973) 205 178 18 9 0.263
Grade 2 22 (11%) 22 (12%) 0 (0%) 0 (0%)  
Grade 3 183 (89%) 156 (88%) 18 (100%) 9 (100%)  
Grade (2004)      
Low-grade 0% 0% 0% 0%  
High-grade 100% 100% 100% 100%  
pN 205 178 18 9 0.743
pN0 90 (44%) 80 (45%) 6 (33%) 4 (44.4%)  
pN1 45 (22%) 40 (22.5%) 3 (17%) 2 (22.2%)  
pN2 69 (33.5%) 57 (32%) 9 (50%) 3 (33.3%)  
pN3 1 (0.5%) 1 (0.5%) 0 (0%) 0 (0%)  
pM 205 178 18 9 1.000
pM0 204 (99.5%) 177 18 (100%) 9 (100%)  
pM1 1 (0.5%) 1 0 (0%) 0 (0%)  
Chemotherapy 205 178 18 9 0.043
Gc 39 39 (%) 0 (0%) 0 (0%)  
M-vec 80 64 (%) 11 (61%) 5 (55%)  
Cm 86 75 (%) 7 (39%) 4 (45%)  
Survival 205 178 18 9 0.061
Alive 120 109 6 (33.3%) 5 (55%)  
Dead 85 69 12 (66.6%) 4 (45%)  
  1. Abbreviations: Gc - Gemcitabine, cisplatin, M-vec - Methotrexate, vinblastine, epirubicin and cisplatin, Cm – Cisplatin, methotrexate.
  2. * statistical test: Fisher’s exact test.
  3. ** statistical test: t-test.