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Table 3 Correlation between serum p53Abs and clinicopathologic parameters, distinguishing between subjects with normal or altered LFT

From: Serum p53 antibody detection in patients with impaired lung function

  Normal LFT p-valuea Altered LFT p-valuea
Age (years) (< 58 / ≥ 58)   (< 58 / ≥ 58)  
Negative 221/154 (59%/ 41%) 0.233 87/174 (33%/67%) 0.938
Positive 15/5 (75%/25%)   4/10 (29%/71%)  
Missing 4   1  
Gender Male / Female   Male / Female  
Negative 202/176 (53%/47%) 0.915 157/105 (60%/40%) 0.136
Positive 12/9 (57%/43%)   12/2 (86%/14%)  
No. of cigarettes per day (> 20 / ≤ 20)   (> 20 / ≤ 20)  
Negative 100/234 (30%/70%) 0.001* 97/122 (44%/56%) 0.904
Positive 14/7 (67%/33%)   5/7 (42%/58%)  
Packs-year (> 40 / ≤ 40)   (> 40 / ≤ 40)  
Negative 105/229 (31%/69%) 0.081# 106/112 (49%/51%) 0.720
Positive 11/10 (52%/48%)   7/5 (58%/42%)  
  1. aCalculated by chi-square test; * p < 0.05, # p < 0.10.