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Table 3 Correlation between serum p53Abs and clinicopathologic parameters, distinguishing between subjects with normal or altered LFT

From: Serum p53 antibody detection in patients with impaired lung function

 

Normal LFT

p-valuea

Altered LFT

p-valuea

Age (years)

(< 58 / ≥ 58)

 

(< 58 / ≥ 58)

 

Negative

221/154 (59%/ 41%)

0.233

87/174 (33%/67%)

0.938

Positive

15/5 (75%/25%)

 

4/10 (29%/71%)

 

Missing

4

 

1

 

Gender

Male / Female

 

Male / Female

 

Negative

202/176 (53%/47%)

0.915

157/105 (60%/40%)

0.136

Positive

12/9 (57%/43%)

 

12/2 (86%/14%)

 

No. of cigarettes per day

(> 20 / ≤ 20)

 

(> 20 / ≤ 20)

 

Negative

100/234 (30%/70%)

0.001*

97/122 (44%/56%)

0.904

Positive

14/7 (67%/33%)

 

5/7 (42%/58%)

 

Packs-year

(> 40 / ≤ 40)

 

(> 40 / ≤ 40)

 

Negative

105/229 (31%/69%)

0.081#

106/112 (49%/51%)

0.720

Positive

11/10 (52%/48%)

 

7/5 (58%/42%)

 
  1. aCalculated by chi-square test; * p < 0.05, # p < 0.10.