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Figure 3 | BMC Cancer

Figure 3

From: Berberine suppresses tumorigenicity and growth of nasopharyngeal carcinoma cells by inhibiting STAT3 activation induced by tumor associated fibroblasts

Figure 3

Constitutive activation of STAT3 was downregulated by berberine in HONE1 cells. HONE1 cells were treated with 25 and 50 μM berberine for 24 h. The activation of STAT3 was strongly suppressed by the treatment of berberine with a downregulation of survival protein (Mcl-1) and upregulation of apoptotic protein (cleaved-PARP-1). β-actin was probed for loading controls.

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