From: Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme
Variable | Haz. ratio | p-value | [95% Conf. Interval] | |
---|---|---|---|---|
Sex | ||||
male | 1.457 | 0.276 | 0.740 | 2.866 |
(ref. female) | 1.130 | 0.793 | 0.454 | 2.813 |
4.222 | 0.043 | 1.045 | 17.060 | |
Age | ||||
50- < 60 years | 1.793 | 0.282 | 0.619 | 5.191 |
(ref. <50 years) | 1.500 | 0.490 | 0.474 | 4.742 |
5.358 | 0.234 | 0.338 | 84.863 | |
Age | ||||
60- < 70 years | 2.474 | 0.066 | 0.942 | 6.499 |
(ref. <50 years) | 2.235 | 0.140 | 0.768 | 6.507 |
3.596 | 0.290 | 0.336 | 38.441 | |
Age | ||||
≥70 years | 6.069 | 0.001 | 2.107 | 17.479 |
(ref. <50 years) | 9.872 | 0.000 | 2.786 | 34.988 |
5.112 | 0.167 | 0.505 | 51.721 | |
Mean methylation level (continuous) | ||||
0.995 | 0.461 | 0.981 | 1.009 | |
1.002 | 0.864 | 0.984 | 1.020 | |
0.973 | 0.032 | 0.950 | 0.998 |