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Table 1 Concordance of test results in routine diagnostic HER2 assays in breast cancer

From: Assessment of HER2 status in breast cancer: overall positivity rate and accuracy by fluorescence in situ hybridization and immunohistochemistry in a single institution over 12 years: a quality control study

 

IHC

   

FISH

0

1+

2+

3+

Non amplified

35

273

413

69

(90%)

(95%)

(87%)

(31%)

Amplified

4

15

63

152

(10%)

(5%)

(13%)

(69%)

Total (n = 1024)

39

288

476

221

(100%)

(100%)

(100%)

(100%)

  1. Immunohistochemistry (IHC) and FISH between 2001 and 2004.