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Table 2 Grade 3 and 4 adverse events: NCI CTC v.3

From: Bifractionated CPT-11 with LV5FU2 infusion (FOLFIRI-3) in combination with bevacizumab: clinical outcomes in first-line metastatic colorectal cancers according to plasma angiopoietin-2 levels

 

Induction chemotherapy

Maintenance chemotherapy

(N = 61)

(N = 41)

Adverse events

No. of patients

%

No. of patients

%

Nausea

1

2

0

-

Vomiting

1

2

0

-

Diarrhea

9

15

2

5

Mucositis

0

-

0

-

Fatigue

6

10

1

2

Platelet count decreased

0

-

0

-

Anemia

0

-

0

-

White blood cell decreased

3

5

0

-

Neutropenia

8

13

0

-

(2 grade IV)

Febrile neutropenia

1

2

0

-

Hypertension

3

5

1

2

Hemorrhage

1

2

0

-

Thromboembolic event

0

-

1*

2

Palmar-plantar syndrome

0

-

6

15

  1. *One catheter related deep vein thrombosis.
  2. Grade IV toxicity: the only grade IV toxicity observed was neutropenia.
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BMC Cancer

ISSN: 1471-2407

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