Table 2 Associations of TP53 SNPs with lung cancer risk in Taiyuan lung cancer study in total study population

TP53 rs2078486

355

448

CC

186

52.4

250

55.8

1

1

TC

136

38.3

167

37.3

1.10 (0.82, 1.47)

1.20 (0.88, 1.64)

TT

33

9.3

31

6.9

1.43 (0.85, 2.42)

1.30 (0.75, 2.25)

Dominant model

Any T vs. CC

169

47.6

198

44.2

1.15 (0.87, 1.52)

1.22 (0.91, 1.63)

Recessive model

TT vs. Any C

33

9.3

31

6.9

1.38 (0.83, 2.30)

1.20 (0.70, 2.06)

Allele OR

T vs. C

1.15 (0.93, 1.43)

1.17 (0.93, 1.46)

TP53 rs1042522

363

446

GG

118

32.5

161

36.1

1

1

CG

146

40.2

196

43.9

1.02 (0.74, 1.40)

1.07 (0.77, 1.50)

CC

99

27.3

89

20.0

1.52 (1.05, 2.20)

1.63 (1.10, 2.41)

Dominant model

Any C vs. GG

245

67.5

285

63.9

1.17 (0.88, 1.57)

1.24 (0.92, 1.69)

Recessive model

CC vs. Any G

99

27.3

89

20.0

1.50 (1.08, 2.09)

1.57 (1.11, 2.21)

Allele OR

C vs. G

1.21 (1.01, 1.46)

1.26 (1.04, 1.53)