Symptom
|
Sample size
|
Age group
|
Mean score
|
Frequency ratings† (%)
|
Unadjusted values
|
Adjusted values
|
---|
Older age
|
Older age
|
---|
1
|
2
|
3
|
4
|
OR
|
CI
|
p-value
|
OR
|
CI
|
p-value
|
---|
Difficulty concentrating
|
150
|
<60
|
2.19
|
22.7
|
44.0
|
25.3
|
8.0
|
.78
|
.50-1.21
|
.269
|
.76
|
.46-1.25
|
.277
|
122
|
≥60
|
2.08
|
24.6
|
50.8
|
16.4
|
8.2
|
Pain
|
192
|
<60
|
2.64
|
13.0
|
33.3
|
30.2
|
23.4
|
.96
|
.67-1.38
|
.829
|
.95
|
.63-1.44
|
.825
|
188
|
≥60
|
2.62
|
14.9
|
32.4
|
28.7
|
23.9
|
Lack of energy
|
215
|
<60
|
2.82
|
5.1
|
30.2
|
42.3
|
22.3
|
.88
|
.62-1.23
|
.446
|
.77
|
.53-1.13
|
.179
|
228
|
≥60
|
2.74
|
10.5
|
32.0
|
30.3
|
27.2
|
Cough
|
106
|
<60
|
2.12
|
26.4
|
41.5
|
25.5
|
6.6
|
.98
|
.61-1.59
|
.937
|
.72
|
.42-1.25
|
.246
|
117
|
≥60
|
2.12
|
26.5
|
42.7
|
23.1
|
7.7
|
Feeling nervous
|
104
|
<60
|
2.13
|
22.1
|
48.1
|
24.0
|
5.8
|
.57
|
.33-.97
|
.038
|
.52
|
.27-.99
|
.046
|
88
|
≥60
|
1.92
|
35.2
|
45.5
|
11.4
|
8.0
|
Dry mouth
|
115
|
<60
|
2.66
|
13.9
|
26.1
|
40.0
|
20.0
|
.66
|
.42-1.03
|
.070
|
.52
|
.32-.85
|
.009
|
139
|
≥60
|
2.44
|
20.9
|
31.7
|
30.2
|
17.3
|
Nausea
|
100
|
<60
|
2.23
|
23.0
|
40.0
|
28.0
|
9.0
|
.55
|
.32-.94
|
.028
|
.54
|
.29-.99
|
.047
|
85
|
≥60
|
1.95
|
34.1
|
43.5
|
15.3
|
7.1
|
Feeling drowsy
|
171
|
<60
|
2.40
|
11.7
|
44.4
|
36.3
|
7.6
|
.82
|
.56-1.22
|
.338
|
.65
|
.42-1.01
|
.058
|
176
|
≥60
|
2.34
|
11.9
|
52.3
|
25.6
|
10.2
|
Numbness/tingling in hands/feet
|
95
|
<60
|
2.63
|
16.8
|
36.8
|
12.6
|
33.7
|
1.08
|
.65-1.81
|
.771
|
.94
|
.52-1.72
|
.846
|
94
|
≥60
|
2.68
|
20.2
|
23.4
|
24.5
|
31.9
|
Difficulty sleeping
|
168
|
<60
|
2.70
|
9.5
|
32.1
|
37.5
|
20.8
|
.88
|
.59-1.32
|
.541
|
.64
|
.41-1.02
|
.058
|
147
|
≥60
|
2.63
|
9.5
|
32.7
|
42.9
|
15.0
|
Feeling bloated
|
84
|
<60
|
2.39
|
22.6
|
32.1
|
28.6
|
16.7
|
.54
|
.29-.98
|
.042
|
.49
|
.24-.99
|
.046
|
63
|
≥60
|
2.06
|
28.6
|
47.6
|
12.7
|
11.1
|
Problems with urination
|
56
|
<60
|
2.39
|
21.4
|
33.9
|
28.6
|
16.1
|
1.52
|
.84-2.73
|
.164
|
1.29
|
.68-2.46
|
.438
|
119
|
≥60
|
2.61
|
11.8
|
33.6
|
37.0
|
17.6
|
Vomiting
|
46
|
<60
|
1.87
|
39.1
|
41.3
|
13.0
|
6.5
|
.85
|
.38-1.93
|
.705
|
.46
|
.15-1.38
|
.165
|
36
|
≥60
|
1.81
|
44.4
|
36.1
|
13.9
|
5.6
|
Shortness of breath
|
99
|
<60
|
2.17
|
19.2
|
52.5
|
20.2
|
8.1
|
1.30
|
.78-2.14
|
.311
|
.97
|
.55-1.70
|
.916
|
106
|
≥60
|
2.35
|
25.5
|
34.0
|
20.8
|
19.8
|
Diarrhea
|
57
|
<60
|
2.12
|
22.8
|
47.4
|
24.6
|
5.3
|
.56
|
.29-1.10
|
.094
|
.47
|
.21-1.03
|
.059
|
72
|
≥60
|
1.89
|
29.2
|
55.6
|
12.5
|
2.8
|
Feeling sad
|
137
|
<60
|
2.05
|
28.5
|
42.3
|
24.8
|
4.4
|
.99
|
.62-1.59
|
.978
|
.79
|
.46-1.36
|
.386
|
103
|
≥60
|
2.08
|
27.2
|
47.6
|
15.5
|
9.7
|
Sweats
|
119
|
<60
|
2.39
|
16.8
|
37.0
|
36.1
|
10.1
|
.66
|
.41-1.07
|
.093
|
.64
|
.37-1.12
|
.121
|
103
|
≥60
|
2.21
|
22.3
|
44.7
|
22.3
|
10.7
|
Worrying
|
152
|
<60
|
2.41
|
9.9
|
52.0
|
25.0
|
13.2
|
.59
|
.36-.94
|
.028
|
.63
|
.37-1.08
|
.094
|
106
|
≥60
|
2.20
|
22.6
|
48.1
|
16.0
|
13.2
|
Problems with sexual interest
|
93
|
<60
|
2.86
|
15.1
|
23.7
|
21.5
|
39.8
|
1.07
|
.61-1.86
|
.821
|
1.04
|
.53-2.02
|
.916
|
74
|
≥60
|
2.89
|
17.6
|
17.6
|
23.0
|
41.9
|
Itching
|
90
|
<60
|
2.38
|
14.4
|
46.7
|
25.6
|
13.3
|
.72
|
.41-1.27
|
.254
|
.71
|
.38-1.33
|
.289
|
76
|
≥60
|
2.21
|
23.7
|
40.8
|
26.3
|
9.2
|
Lack of appetite
|
100
|
<60
|
2.44
|
18.0
|
39.0
|
24.0
|
19.0
|
1.44
|
.88-2.38
|
.149
|
1.16
|
.66-2.05
|
.598
|
101
|
≥60
|
2.64
|
18.8
|
24.8
|
29.7
|
26.7
|
Dizziness
|
71
|
<60
|
1.82
|
39.4
|
40.8
|
18.3
|
1.4
|
.96
|
.52-1.78
|
.902
|
.78
|
.38-1.61
|
.502
|
70
|
≥60
|
1.81
|
38.6
|
45.7
|
11.4
|
4.3
|
Difficulty swallowing
|
43
|
<60
|
2.23
|
30.2
|
32.6
|
20.9
|
16.3
|
.87
|
.41-1.81
|
.701
|
.56
|
.23-1.38
|
.207
|
50
|
≥60
|
2.14
|
32.0
|
34.0
|
22.0
|
12.0
|
Feeling irritable
|
136
|
<60
|
1.99
|
30.1
|
44.1
|
22.1
|
3.7
|
.78
|
.48-1.25
|
.300
|
.67
|
.38-1.17
|
.161
|
105
|
≥60
|
1.88
|
33.3
|
47.6
|
17.1
|
1.9
|
Mouth sores
|
39
|
<60
|
2.21
|
38.5
|
28.2
|
7.7
|
25.6
|
.73
|
.33-1.63
|
.447
|
.75
|
.29-1.93
|
.553
|
42
|
≥60
|
2.02
|
47.6
|
23.8
|
7.1
|
21.4
|
Change in way food tastes
|
80
|
<60
|
2.54
|
17.5
|
31.3
|
31.3
|
20.0
|
1.11
|
.65-1.88
|
.709
|
1.16
|
.65-2.08
|
.616
|
98
|
≥60
|
2.60
|
16.3
|
33.7
|
23.5
|
26.5
|
Weight loss
|
59
|
<60
|
2.07
|
22.0
|
55.9
|
15.3
|
6.8
|
.76
|
.40-1.44
|
.400
|
.56
|
.27-1.16
|
.120
|
75
|
≥60
|
1.99
|
34.7
|
41.3
|
14.7
|
9.3
|
Hair loss
|
62
|
<60
|
2.85
|
16.1
|
22.6
|
21.0
|
40.3
|
1.02
|
.53-1.95
|
.953
|
.89
|
.43-1.84
|
.745
|
60
|
≥60
|
2.85
|
21.7
|
15.0
|
20.0
|
43.3
|
Constipation
|
89
|
<60
|
2.53
|
14.6
|
40.4
|
22.5
|
22.5
|
.82
|
.49-1.38
|
.455
|
.87
|
.49-1.53
|
.626
|
102
|
≥60
|
2.42
|
15.7
|
45.1
|
20.6
|
18.6
|
Swelling of arms or legs
|
43
|
<60
|
2.67
|
23.3
|
23.3
|
16.3
|
37.2
|
1.04
|
.51-2.15
|
.906
|
.91
|
.39-2.12
|
.832
|
54
|
≥60
|
2.70
|
24.1
|
20.4
|
16.7
|
38.9
|
I don’t look like myself
|
92
|
<60
|
2.67
|
15.2
|
29.3
|
28.3
|
27.2
|
.79
|
.45-1.39
|
.420
|
.84
|
.45-1.57
|
.587
|
69
|
≥60
|
2.54
|
20.3
|
27.5
|
30.4
|
21.7
|
Changes in skin
|
100
|
<60
|
2.77
|
15.0
|
24.0
|
30.0
|
31.0
|
.69
|
.39-1.20
|
.188
|
.97
|
.52-1.82
|
.929
|
67
|
≥60
|
2.54
|
23.9
|
25.4
|
23.9
|
26.9
|
- Abbreviations: CI, confidence interval; OR, odds ratio.
- †Frequency ratings = rarely (1), occasionally (2), frequently (3), almost constantly (4).