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Table 3 Pooled ORs and 95% CIs for ERCC2 rs13181 polymorphism of stratified meta-analysis

From: Association between polymorphisms in ERCC2 gene and oral cancer risk: evidence from a meta-analysis

Subgroup Genotype No of studies Test of association Test of heterogeneity
    OR(95% CI) Z P-value Model χ 2 P-value I2(%)
Asian AC vs. AA 4 1.16[0.88,1.36] 0.83 0.405 F 5.81 0.121 48.3
  CC vs. AA 4 1.33[0.59,3.01] 0.69 0.489 R 1.41 0.098 52.3
AC + CC vs. AA 4 1.13[0.75,1.71] 0.59 0.555 R 8.79 0.032 65.9
CC vs. AC + AA 4 1.08[0.74,1.56] 0.39 0.694 F 4.36 0.225 61.2
  C vs. A 4 1.12[0.76,1.65] 0.56 0.576 R 10.90 0.012 72.5
Oral leukoplakia AC vs. AA 4 1.28[1.01,1.62] 2.01 0.045 F 2.13 0.546 0.0
  CC vs. AA 4 1.94[0.99,3.79] 1.95 0.052 R 7.52 0.057 60.1
AC + CC vs. AA 4 1.35[1.08,1.69] 2.60 0.009 F 3.64 0.303 17.6
CC vs. AC + AA 4 1.67[0.90,3.13] 1.63 0.102 R 7.20 0.066 58.3
  C vs. A 4 1.38[1.04,1.82] 2.26 0.024 R 6.88 0.043 56.4
Oral cancer AC vs. AA 4 1.10[0.73,1.65] 0.45 0.656 R 7.02 0.071 57.3
  CC vs. AA 4 1.07[0.69,1.69] 0.31 0.758 F 5.26 0.154 43.0
AC + CC vs. AA 4 1.11[0.71,1.75] 0.46 0.643 R 9.29 0.026 67.7
CC vs. AC + AA 4 1.01[0.66,1.55] 0.06 0.951 F 3.13 0.371 4.3
  C vs. A 4 1.09[0.73,1.64] 0.44 0.661 R 10.22 0.064 55.0
  1. OR, odds ratio; vs, versus; R, random effect model; F, fixed effect model.