Figure 6
From: The cancer gene WWOX behaves as an inhibitor of SMAD3 transcriptional activity via direct binding
WWOX AND ANGPTL4 expression meta-analysis in breast cancer datasets. Comparative analysis of WWOX and ANGPTL4 expression in three independent gene expression studies of primary breast carcinomas. Unsupervised clustering resulted in two main groups, Cluster 1: WWOX hi /ANGPTL4 lo and Cluster 2 WWOX lo /ANGPTL4 hi according to their gene expression profiles. We identified a statistically significant enrichment of TNBC and basal-like breast carcinomas in cluster 2 from each dataset (p < 0.05).