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Table 4 Univariate and multivariate analysis of variable factors for 5-year metastasis free survival (MFS)

From: Radiographic response to neoadjuvant therapy and its impact on scope of surgery and prognosis in stage IIB/III soft tissue sarcomas

Factors MFS Univariate analysis Multivariate analysis
RR 95% CI P RR 95% CI P
Radiographic response     <0.001    <0.001
 PR (n = 25) 96.0 0.072 0.025-0.209   0.098 0.030-0.317  
 SD + PD (n = 95) 30.9 1    1   
Size (cm)     <0.001    0.991
 ≥10 (n = 63) 29.0 3.098 1.821-5.271   1.004 0.519-1.940  
 <10 (n = 57) 67.9 1    1   
FNCLCC Grade     <0.001    0.008
 Grade 2 (n = 45) 70.2 1    1   
 Grade 3 (n = 75) 33.9 2.938 1.632-5.291   2.391 1.255-4.553  
UICC margins     <0.001    0.001
 R0 + R1 (n = 92) 60.6 1    1   
 R2 (n = 28) 3.6 5.995 3.600-9.983   2.553 1.461-4.462  
Surgery type     <0.001    0.181
 Resection only (n = 55) 75.8 1    1   
 Resection with other modalities* (n = 65) 22.8 4.882 2.725-8.744   1.638 0.795-3.376  
  1. *: Other modalities include epineural dissection and reconstruction of blood vessels and bony structures. FNCLCC: French Federation of Cancer Centres; UICC: Union Internationale Contre Cancer.